Quality Assessment of Ki67 Staining and Using Cell Line Proliferation Index and Stain Intensity Features

Quality Assessment of Ki67 Staining Using Cell Line Proliferation Index and Stain Intensity Features

 

September 17, 2019

 

Presented by:

 

Alex Skovsbo Jørgensen
Assistant Professor
Aalborg University

 

Moderated by Kewal Asosingh, PhD, SCYM(ASCP)

 

About the Presenter

Alex is an assistant professor at Aalborg University at the Department of Health Science and Technology. His research focus is using machine learning and image analysis within the domain of digital pathology. His current research topics of interest within digital pathology is automated cancer detection and grading, artificial intelligence, and quality assessment of staining protocols. 

 

Webinar Summary

Breast cancer is the most frequent cancer among women worldwide. Ki67 can be used as an immunohistochemical pseudo marker for cell proliferation to determine how aggressive the cancer is and thereby the treatment of the patient. No standard Ki67 staining protocol exists, resulting in inter?laboratory stain variability. Therefore, it is important to determine the quality control of a staining protocol to ensure correct diagnosis and treatment of patients. Currently, quality control is performed by the organization NordiQC that use an expert panel?based qualitative assessment system. However, no objective method exists to determine the quality of a staining protocol.

 

Learning Objectvies

  • Understand the challenges of staining quality assessment

  • Use cell lines for assessment of stain quality

  • How to use image analysis and machine learning for quality assessment of staining protocols

  • Understand validation challenges

 

Who Should Attend

Pathologists, engineers within medial image analysis and machine learning

 

 

 

Seminar Information
Date Presented:
September 17, 2019 12:00 PM Eastern
Length:
1 hour
Quality Assessment of Ki67 Staining and Using Cell Line Proliferation Index and Stain Intensity Features
Individual topic purchase: Selected
American Society for Clinical Pathology
CMLE: 1.00
Products
Streaming
ISAC Member Price: $0.00
Non-Member Price:$0.00