Chris Bakal, Ph.D. will be presenting the webinar "The Signaling Networks Regulating Morphological Heterogeneity." Chris is a Dynamical Cell Systems Team Leader in the Division of Cancer Biology at the Institute of Cancer Research in London UK.
The Dynamical Cell Systems Team is using high-throughput functional genomic approaches in tandem with integrative computational technologies to understand the architecture and dynamics of signal transduction networks. He studies the biological switches that cause cells to change shape, become cancerous and spread around the body. By understanding how these switches work, scientists may one day find a way to control them through drugs or other therapies. Cells are able to assume a wide variety of complex shapes in order to carry out different roles and Dr Bakal's team examines the genetic and biochemical mechanisms that underpin these shape changes. Their research covers how both environmental and genetic variation affects cell shape. Ultimately, Dr Bakal aims to understand how normal and cancerous cells can adopt different shapes and why metastatic cancer develops in some people but not others.